Phylogeny and evolution of RNA structure. (2024)

Gesell, T., & Schuster, P. (2014). Phylogeny and evolution of RNA structure. Methods in Molecular Biology, 1097, 319-378. https://doi.org/10.1007/978-1-62703-709-9_16

Gesell, Tanja ; Schuster, Peter. / Phylogeny and evolution of RNA structure. in: Methods in Molecular Biology. 2014 ; Band 1097. S. 319-378.

@article{9ff62ce9198c4934b53eb14e330f00e8,

title = "Phylogeny and evolution of RNA structure.",

abstract = "Darwin's conviction that all living beings on Earth are related and the graph of relatedness is tree-shaped has been essentially confirmed by phylogenetic reconstruction first from morphology and later from data obtained by molecular sequencing. Limitations of the phylogenetic tree concept were recognized as more and more sequence information became available. The other path-breaking idea of Darwin, natural selection of fitter variants in populations, is cast into simple mathematical form and extended to mutation-selection dynamics. In this form the theory is directly applicable to RNA evolution in vitro and to virus evolution. Phylogeny and population dynamics of RNA provide complementary insights into evolution and the interplay between the two concepts will be pursued throughout this chapter. The two strategies for understanding evolution are ultimately related through the central paradigm of structural biology: sequence ⇒ structure ⇒ function. We elaborate on the state of the art in modeling both phylogeny and evolution of RNA driven by reproduction and mutation. Thereby the focus will be laid on models for phylogenetic sequence evolution as well as evolution and design of RNA structures with selected examples and notes on simulation methods. In the perspectives an attempt is made to combine molecular structure, population dynamics, and phylogeny in modeling evolution.",

keywords = "Evolution of structure, Multiple structures, Phylogeny, Quasispecies concept, Sequence evolution, Sequence-structure mappings, Simulations",

author = "Tanja Gesell and Peter Schuster",

note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2014.",

year = "2014",

month = jan,

day = "1",

doi = "10.1007/978-1-62703-709-9_16",

language = "English",

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pages = "319--378",

journal = "Methods in Molecular Biology",

issn = "1064-3745",

publisher = "Humana Press",

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Gesell, T & Schuster, P 2014, 'Phylogeny and evolution of RNA structure.', Methods in Molecular Biology, Jg. 1097, S. 319-378. https://doi.org/10.1007/978-1-62703-709-9_16

Phylogeny and evolution of RNA structure. / Gesell, Tanja; Schuster, Peter.

in: Methods in Molecular Biology, Band 1097, 01.01.2014, S. 319-378.

Veröffentlichungen: Beitrag in Fachzeitschrift › Artikel › Peer Reviewed

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Gesell T, Schuster P. Phylogeny and evolution of RNA structure. Methods in Molecular Biology. 2014 Jan 1;1097:319-378. doi: 10.1007/978-1-62703-709-9_16